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Due et al., Evidence supports that after a central nervous system injury, increased extracellular glutamate levels activate several intracellular pathways including ROS formation

Effective date 2024-03-10 Source Legacy FDA.report DailyMed cache The current SPL XML is not hydrated on this host yet for this set

However, investigations conducted to date have been through animal or in vitro studies, which have produced largely conflicting results

The ototoxicity of cisplatin is permanent sensorineural hearing loss due to the major damage to the spiral apparatus (Corti organ), spiral ganglion neurons (SGN) and vascular striae (Rybak et al., 2019

Decreases were also detected in 1- and 4-month-olds at 3 hours after CCI injury (Durham et al., 2000)